LONG-TERM EXPANSION OF BASAL CELLS AND THE NOVEL DIFFERENTIATION METHODS IDENTIFY MECHANISMS FOR SWITCHING CLAUDIN EXPRESSION IN NORMAL EPITHELIA

Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia

Abstract Epithelia are tightly connected cellular sheets, that TRAINING shield our body from the external environment.They are continuously maintained by a pooled population of undifferentiated cells through differentiation.However, the maintenance mechanisms remain incompletely understood due to the difficulty of experimentally observing the diffe

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Jabuticaba [Plinia trunciflora (O. Berg) Kausel] Protects Liver of Diabetic Rats Against Mitochondrial Dysfunction and Oxidative Stress Through the Modulation of SIRT3 Expression

Complications generated by hyperglycemia present in diabetes mellitus (DM) have been constantly related to oxidative stress and dysfunction in the mitochondrial electron transport chain (ETC).Sirtuin 3 (SIRT3), which is present in mitochondria, is responsible for regulating several proteins involved in metabolic homeostasis and oxidative stress.Stu

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Automatic single fish detection with a commercial echosounder using YOLO v5 and its application for echosounder calibration

Nowadays, most fishing vessels are equipped with high-resolution commercial echo sounders.However, many instruments cannot be calibrated and missing data occur frequently.These problems impede the collection of acoustic data by commercial fishing vessels, which are necessary for species classification and stock assessment.In this study, an Holiday

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